In general, there are two groups of vaccines. The first are live attenuated vaccines (this includes live bacteria or virus that have lost their power to trigger disease) and inactive or recombinant vaccines (includes killed dead organisms or simply some of their components in a pure form).
|Live attenuated vaccines||Inactivated or recombinant|
Live attenuated vaccines are generally not recommended in patients who take cortisone orally, intramuscularly or via intravenous routes. The U.S. Department of Health believes that this holds especially true for patients receiving more than 20 mg per day of prednisone for longer than two weeks. It is therefore recommended to wait a few weeks after stopping corticosteroids before using such a vaccine.
Inactive or recombinant vaccines can be used safely in patients treated with cortisone. Although your immune response could be modified, corticosteroid therapy does not inhibit the effectiveness of these vaccines.
According to many national and international recommendations, patients exposed for systemic glucocorticoids for several weeks or months should be adequately vaccinated against influenza and pneumococcus.
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lastest update : February 20 2019