Vaccines

Vaccines In general, there are two groups of vaccines. The first are live attenuated vaccines (this includes live bacteria or virus that have lost their power to trigger disease) and inactive or recombinant vaccines (includes killed dead organisms or simply some of their components in a pure form). Live attenuated vaccines Inactivated or [...]

2024-03-21T14:20:51+01:00March 20th, 2024|Tags: , , , |

Sport

Sport and doping Cortisone can improve the mental and physical abilities of athletes and are therefore considered "doping" substances. Corticosteroids taken as tablets, through intramuscular or intravenous injection, and even rectally are prohibited (except in certain cases) for the majority of competitive athletes. Athletes benefit from certain properties of steroids including: Increased effort [...]

2024-03-21T14:21:16+01:00March 20th, 2024|Tags: , , , |

Contraception

Contraception Cortisone does not interact with birth control pills (either estrogen-progestin or progestogen). There is no indication of potential harm caused by the use of corticosteroids and birth control at the same time. Old studies have argued that, due to cortisone's anti-inflammatory properties, it may decrease the effectiveness of an IUD (intrauterine device). [...]

2024-03-21T14:22:13+01:00March 20th, 2024|Tags: , , , , |

Surgery

Surgery Your doctor may prescribe a short-term cortisone treatment during and after a surgery. This is in order to minimize nausea/vomiting and post-operative pain. This specific type of short-term treatment does not lead to an increased risk of infection nor does it alter the progress/quality of healing. However, because of the increased risk [...]

2024-03-21T14:22:44+01:00March 20th, 2024|Tags: , , |

Children

Children Adverse side effects observed in children are similar to those observed in adults. On top of that, corticosteroids can cause long-term growth retardation in young children. Cortisone is often given to children on alternating days in order to limit adverse effects such as these. A child treated with corticosteroids may attend school [...]

2024-03-21T14:24:27+01:00March 20th, 2024|Tags: , , , , |

Associated measures other than medications

Measures that do not involve specific drugs are also recommended Your doctor may prescribe a specific diet. It should not be too restrictive and will be adapted for each patient's specific case. Regular physical activity is highly recommended in order to limit the risk of muscle wasting, weight gain and osteoporosis caused by [...]

2024-03-21T14:41:44+01:00March 20th, 2024|Tags: , , , , |

Steroid dependence/withdrawal syndrome

Long-term cortisone use can lead a patient to become dependent on the substance. The body develops a tolerance to the drug and quickly needs it to function. A physical or psychological dependence on cortisone can be observed. When treatment is discontinued, feelings of anxiety and/or symptoms that suggest depression may occur. When these [...]

2024-03-21T14:20:23+01:00March 20th, 2024|Tags: , , , |

Useful references

Useful websites Textbooks information about glucocorticoids: www.vidal.fr (French national dictionnary about drugs informations) www.lecrat.fr (French national center about teratogenic drugs) www.dianafoundation.com (US fondation about glucocorticoids and their side effects)   information about vasculitis: www.VasculitisFoundation.org www.pmrgcauk.com  www.vasculitis.org.uk     information about connective tissue diseases and sarcoidosis: www.sclerodermasociety.co.uk www.sila.org.uk www.sarcoidosisnetwork.org     information about rheumatological [...]

2024-03-21T14:21:44+01:00March 20th, 2024|Tags: , |

Weight gain and changes in physical appearance

Weight and physical appearance Description: corticosteroids are known to frequently cause weight gain in patients. This gain is is usually moderate, consisting of 1 to 2 kilograms of added mass. In addition, corticosteroids enlarge certain aspects of the face. A "moon face" can result, meaning a large forehead and a large chin appear [...]

Specific properties of inhaled corticosteroids

Inhaled corticosteroids Inhaled corticosteroids, while much better tolerated by patients compared to pills or injections, may also cause side effects when taken for several months at high doses. These effects can include cataracts, osteoporosis and adrenal insufficiency. However, these side effects are very rare. Moreover, when taken orally in the airways, corticosteroids can [...]

2024-03-21T14:30:25+01:00March 20th, 2024|Tags: , , , , , |
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