What is Cortisone ?

What is cortisone ? Above each individual's kidney lies the small, pyramid-shaped adrenal gland. The adrenal gland consists of two parts, each with a specific function. The central part is called the adrenal medulla (or medulla) and the outer portion is called the adrenal cortex (or cortex) These two parts of the gland [...]

2019-08-06T15:08:09+02:00July 12th, 2019|Tags: , |

Vaccines

Vaccines In general, there are two groups of vaccines. The first are live attenuated vaccines (this includes live bacteria or virus that have lost their power to trigger disease) and inactive or recombinant vaccines (includes killed dead organisms or simply some of their components in a pure form). Live attenuated vaccines Inactivated or [...]

2019-08-06T15:47:35+02:00July 7th, 2019|Tags: , , , |

Sport

Sport and doping Cortisone can improve the mental and physical abilities of athletes and are therefore considered "doping" substances. Corticosteroids taken as tablets, through intramuscular or intravenous injection, and even rectally are prohibited (except in certain cases) for the majority of competitive athletes. Athletes benefit from certain properties of steroids including: Increased effort [...]

2019-08-06T15:49:31+02:00July 7th, 2019|Tags: , , , |

Contraception

Contraception Cortisone does not interact with birth control pills (either estrogen-progestin or progestogen). There is no indication of potential harm caused by the use of corticosteroids and birth control at the same time. Old studies have argued that, due to cortisone's anti-inflammatory properties, it may decrease the effectiveness of an IUD (intrauterine device). [...]

2019-08-06T15:52:08+02:00July 7th, 2019|Tags: , , , , |

Surgery

Surgery Your doctor may prescribe a short-term cortisone treatment during and after a surgery. This is in order to minimize nausea/vomiting and post-operative pain. This specific type of short-term treatment does not lead to an increased risk of infection nor does it alter the progress/quality of healing. However, because of the increased risk [...]

2019-08-06T15:54:09+02:00July 7th, 2019|Tags: , , |

Children

Children Adverse side effects observed in children are similar to those observed in adults. On top of that, corticosteroids can cause long-term growth retardation in young children. Cortisone is often given to children on alternating days in order to limit adverse effects such as these. A child treated with corticosteroids may attend school [...]

2019-08-06T15:55:46+02:00July 7th, 2019|Tags: , , , , |

Steroid dependence/withdrawal syndrome

Long-term cortisone use can lead a patient to become dependent on the substance. The body develops a tolerance to the drug and quickly needs it to function. A physical or psychological dependence on cortisone can be observed. When treatment is discontinued, feelings of anxiety and/or symptoms that suggest depression may occur. When these [...]

2019-08-06T16:03:30+02:00July 7th, 2019|Tags: , , , |

Useful references

Useful websites Textbooks information about glucocorticoids: www.vidal.fr (French national dictionnary about drugs informations) www.lecrat.fr (French national center about teratogenic drugs) www.dianafoundation.com (US fondation about glucocorticoids and their side effects)   information about vasculitis: www.VasculitisFoundation.org www.pmrgcauk.com  www.vasculitis.org.uk     information about connective tissue diseases and sarcoidosis: www.sclerodermasociety.co.uk www.sila.org.uk www.sarcoidosisnetwork.org     information about rheumatological [...]

2019-08-06T10:00:20+02:00July 7th, 2019|Tags: , |

Bone Issues

Bone side effects Description: skeletal complications upon being treated with corticosteroids therapy are generally of two main types: Ostéoporose Osteoporosis (= fragile bones). At later stages, osteoporosis increases the risk of fractures, including those of the vertebrae and the femur. Fractures of the vertebrae can occur after trauma or simply spontaneously [...]

2019-08-06T15:16:11+02:00July 7th, 2019|Tags: , , , , , |

Side effects on muscles and tendons

Muscles and tendons Description: corticosteroids weaken muscles and tendons. Myopathy can affect patients in the form of muscle weakness and can become troublesome in everyday life (climbing stairs, lifting). Usually, there is no muscle pain. Cortisone can also weaken the tendons but symptoms are usually non-existent and cases of tendon rupture are rare. [...]

2019-08-02T11:54:06+02:00July 7th, 2019|Tags: , , , , , |