Mood changes Description: mood changes caused by corticosteroids are usually minors (e.g. insomnia, anxiety, irritablity, short-term memory loss and difficulty concentrating). In very rare cases, severe symptoms do appear (e.g. depression, delusions, euphoria). Frequency : minor mood changes are commonplace. For example, 40 to 50% of patients reported insomnia, irritability or anxiety. Severe [...]